Maria del Pilar Martinez Viedma, PhD

Post-Doctoral Fellow


858-200-1812

Bio

I am a Postdoctoral Researcher with a strong background in Microbiology, Molecular Biology, Virology and Immunology. I have experience working in diverse settings where I applied my knowledge and acquired cutting edge techniques that are reflected in my strong publication record.

I gained great part of my technical skills and knowledge in Microbiology and Bacteriology during my Ph.D. training at the University of Jaen (Spain) where Dr. Antonio Gálvez mentored me. My thesis was focused on food safety with the study of bacteriocines as a natural preservative against food pathogens such as B. cereus, S. aureus, L. monocytogenes among other pathogenic bacteria. My undergraduate studies were funded by a Fellowship from the University of Jaen in Spain. I also obtained the European Doctorate Mention as a result of an exchange stay in the laboratory of Dr. Danilo Ercolini (University of Naples Federico II, Italy).

As a Postdoctoral Fellow in the Infectious Diseases Department at the Boston Children’s Hospital, Harvard Medical School, I continued expanding my knowledge in Molecular Biology, Virology and Immunology. I investigated the molecular mechanisms by which SIV (Simian Immunodeficiency Virus) cause AIDS in non-naturally infected non-human primates, and I compared the outcome of this infection to naturally SIV-infected non-human primates, where SIV infection does not lead to AIDS. Particularly, I studied gene expression and cellular pathways activated in macrophages from these two different models.

Throughout my experience and training, I have gained a unique perspective in approaching a broad range of projects, people and environments.

Research Priorities

  • To identify immunodominant epitopes for multiple Flavivirus species.
  • To design, develop, and implement a seroimmune diagnostic method for ZIKV detection, based on the detection of specific epitopes from the virus.
  • To determine ZIKV seroprevalence in serum samples collected from outbreak regions.
HIV-1 Tat second exon limits the extent of Tat-mediated modulation of interferon-stimulated genes in antigen presenting cells.
Retrovirology. 2014-04-17; 11.30.
PMID: 24742347
Resistance to infection, early and persistent suppression of simian immunodeficiency virus SIVmac251 viremia, and significant reduction of tissue viral burden after mucosal vaccination in female rhesus macaques.
Journal of virology. 2014-01-01; 88.1: 212-24.
PMID: 24155376
Tat engagement of p38 MAP kinase and IRF7 pathways leads to activation of interferon-stimulated genes in antigen-presenting cells.
Blood. 2013-05-16; 121.20: 4090-100.
PMID: 23535064
Increased inactivation of exopolysaccharide-producing Pediococcus parvulus in apple juice by combined treatment with enterocin AS-48 and high-intensity pulsed electric field.
Journal of food protection. 2010-01-01; 73.1: 39-43.
PMID: 20051202
Antistaphylococcal effect of enterocin AS-48 in bakery ingredients of vegetable origin, alone and in combination with selected antimicrobials.
Journal of food science. 2009-09-01; 74.7: M384-9.
PMID: 19895485
Effect of enterocin AS-48 in combination with high-intensity pulsed-electric field treatment against the spoilage bacterium Lactobacillus diolivorans in apple juice.
Food microbiology. 2009-08-01; 26.5: 491-6.
PMID: 19465245
Assay of enterocin AS-48 for inhibition of foodborne pathogens in desserts.
Journal of food protection. 2009-08-01; 72.8: 1654-9.
PMID: 19722396
The effect of adding antimicrobial peptides to milk inoculated with Staphylococcus aureus and processed by high-intensity pulsed-electric field.
Journal of dairy science. 2009-06-01; 92.6: 2514-23.
PMID: 19447982
Inactivation of Geobacillus stearothermophilus in canned food and coconut milk samples by addition of enterocin AS-48.
Food microbiology. 2009-05-01; 26.3: 289-93.
PMID: 19269571
Antibacterial protection by enterocin AS-48 in sport and energy drinks with less acidic pH values.
Journal of food protection. 2009-04-01; 72.4: 881-4.
PMID: 19435243
Enhanced bactericidal effect of enterocin AS-48 in combination with high-intensity pulsed-electric field treatment against Salmonella enterica in apple juice.
International journal of food microbiology. 2008-12-10; 128.2: 244-9.
PMID: 18829125
Comparative analysis of genetic diversity and incidence of virulence factors and antibiotic resistance among enterococcal populations from raw fruit and vegetable foods, water and soil, and clinical samples.
International journal of food microbiology. 2008-03-31; 123.1-2: 38-49.
PMID: 18180067